Antimicrobial Resistance

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Antimicrobial agents are essential drugs to combat infections in humans and animals. In recent decades, the world has been confronted with the accelerated emergence of resistant bacteria, viruses and parasites due to the overuse and misuse of antimicrobial agents. Antimicrobial resistance (AMR) is currently posing an extraordinary threat not only to human and animal health, but also to the world ecosystem. A shared responsibility from the human, animal and plant sectors is required to minimize pressure for the selection of AMR factors under the One Health approach from regional, national to international levels.

OIE’s role in combating AMR

  1. Promote responsible and prudent use of antimicrobial agents to preserve their therapeutic efficacy and prolong their use in both animals and humans
  2. Develop inter-departmental standards on AMR
  3. Monitoring the qualities of antimicrobial agents used
  4. Develop standards and guidelines to provide methodologies for OIE member countries to appropriately address the risk of the emergency or spread of resistance bacteria that result from the use of antimicrobial agents in food-producing animals
  5. Build a global database on antimicrobial agents intended for animal use as supported by FAO and WHO within the tripartite collaboration.

OIE Strategy

The OIE Strategy on Antimicrobial Resistance and the Prudent use of Antimicrobials was launched in November 2016 with focus on four objectives of enhancing awareness and understanding; support good governance and capacity building; strengthening knowledge through research and surveillance; and encourage implementation of international standards.

OIE Strategy on AMR and Prudent use of Antimicrobials

International and Intersectoral Collaboration

In recognition of the emerging AMR issues at all levels, the WHO in close collaboration with its tripartite partners, the OIE and the FAO developed the “Global Action Plan on AMR” in 2015 which serves as a strategic framework for Member Countries to develop their national action plans (NAPs) to combat AMR. The action plan was adopted in 2015 by all countries through decisions in the World Health Assembly (WHA), the FAO’s Governing Conference, and the World Assembly of the OIE Delegates.

Global Action Plan on AMR

Regional Activities

The OIE Regional Representation for Asia and the Pacific and the OIE Sub-Regional Representation for South East Asia have been organising activities on AMR and AMU (antimicrobial usage) since 2018 to support the OIE Members in the region drive the agenda of AMR/AMU. The key activities include AMU monitoring workshops to understand the AMU supply chain; awareness seminars for the livestock and aquaculture industries; awareness seminars for the veterinary educations establishments (VEE); laboratory trainings on AMR surveillance; and focal point trainings for veterinary products. The OIE also supports its Members conduct activities during World Antibiotic Awareness Week. AMR is one of the three flagship topics selected for FAO/OIE/WHO tripartite collaboration.

Veterinary services should mainstream antimicrobial stewardship as one of its core activities to combat AMR for which the OIE can provide necessary support.

Communication materials in various languages are available for download.

World Antibiotic Awareness Week

18-24 November 2019

The World Antibiotic Awareness Week is a week to raise awareness of the health risks posed by antibiotic resistance and to promote good practice in this area of concern, in efforts to limit the emergence and spread of resistant bacteria throughout the world.


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Related events


Regional Meeting on Antimicrobial Resistance Control in Animals

October 31, 2018
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OIE Sub-Regional Conference on AMR Related Research and Information

March 07, 2019
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8th Asia-Pacific Workshop on Multi-Sectoral Collaboration

April 09, 2019
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